ISS Pro Evolution is the third video game in the ISS Series produced by Konami for PlayStation. In Japan, it was released as Winning Eleven 4. The engine has been recreated, providing new player movements, animations, and improved graphics.

The new version featured updated player rosters, an extended number of game modes, teams (including club teams for the first time), stadiums, and settings, providing a highly developed player editor.

The replays could be stored on a memory card, as well as won trophies and unlocked bonuses. In this version, the one-two-pass system was refined, becoming one of the greatest threats to the opponent. Dribbling, including trick shooting, was introduced as an element of the gameplay.