Predator 2 is a 1992 second video game adaptation of the film of the same title, developed by Perfect 10 Productions and Teeny Weeny Games and published by Acclaim Entertainment. It was released for the Sega Genesis, Game Gear, and Master System.

The game is played in a third-person isometric view, with great swarms of easily-killed bad guys, who appear through one-way doors scattered throughout the level. Weapons not only include faster machine guns and shotguns, but also a few highly-advanced Predator weapons the player can pick up and use. Each defeated gang member drops drugs that can be picked up and automatically sent off to the "drug squad" for points. No sounds or music from the film get used, but stills scenes from the film do introduce the levels.