World Series Baseball 2K2 features a complete 2002 roster list and various game modes. Players can compete in a standard exhibition game, go for a franchise, skip directly to the playoffs, compete in a home run derby, or play online.

The game features several new options compared to its predecessors. Players can take total control of their fielding and lineup positions. It is possible to create, sign, and trade free agents. The game allows players to manage their batting and pitching rotation. It is also possible to set up a custom batting order and take control of every player on the field.

There are many statistics to keep track of, including hot and cold zones for each player, drafts, injuries, trades and fines.

The title was also released on Xbox under the title "World Series Baseball".